摘要
X光透镜能以较大的收集角收集X光 ,并以准平行光出射 .X光透镜应用于生物蛋白大分子晶体衍射 ,替代单色仪双聚焦镜 ,照射晶体样品的光强提高数倍乃至 1到 2个数量级 ,衍射强度的提高远大于 5倍 ,大大缩短了测试时间 ,分辨能力改善 0 .0 2~ 0 .0 5nm 。
Monolithic polycapillary X ray lens, developed in recent years, has many applications in different fields. Described is a successful application to the X ray diffraction of macromolecular crystallography. By using monolithic X ray lens, the direct beam intensity irradiating on crystal is 1 to 2 order of magnitude higher than the traditional method with double focusing mirrors. The diffracted X ray intensity is increased over 5 times and resolution is improved by 0.02~0.05 nm. Signal to noise ratio is also improved and the time of measurement is reduced. The crystal samples which have to be analyzed by synchrotron radiation before can be investigated by routine laboratory X ray source now.
出处
《北京师范大学学报(自然科学版)》
CAS
CSCD
北大核心
2000年第1期32-34,共3页
Journal of Beijing Normal University(Natural Science)
基金
北京市自然科学基金资助项目!(1972 0 0 1)
关键词
X光透镜
X光衍射
大分子晶体衍射
蛋白
monolithic polycapillary X ray lens
X ray diffraction
macromolecular crystallography diffraction