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高敏C反应蛋白对动脉硬化及心血管事件的早期诊断意义 被引量：6

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摘要 目的探讨高敏C反应蛋白(Hs-CRP)对动脉硬化及心血管事件发生的早期诊断意义。方法 75名动脉硬化患者根据Hs-CRP基线四分位值将其分为4组,比较其空腹血浆Hs-CRP、TC、LDL-C、HDL-C、TG、血糖、临床一般情况及初次就诊和6、12、18、24个月复查时的颈动脉内中膜厚度。结果 BMI、吸烟、收缩期高血压、他汀类药物和2型糖尿病均与Hs-CRP相关(P<0.05),尤以2型糖尿病最明显(r=0.57)。多重线性回归分析模型显示,BMI、吸烟、收缩期高血压、他汀类药物、2型糖尿病和Hs-CRP均与CIMT有关(P<0.01),尤其是Hs-CRP最明显(β=0.57)。24个月随访期间,第4区组CIMT增长最明显。结论 Hs-CRP有独立的动脉硬化和心血管事件预测价值。
作者 师姗姗 刘幼文 金光临 王涓 曾繁芳
机构地区 广东省深圳市孙逸仙心血管医院
出处 《广东医学院学报》 2012年第5期507-509,共3页 Journal of Guangdong Medical College
关键词 高敏C反应蛋白 颈动脉内中膜厚度 心血管事件
分类号 R741 [医药卫生—神经病学与精神病学]
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参考文献11

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共引文献8

同被引文献39

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引证文献6

二级引证文献21

广东医学院学报
2012年 第5期

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