应用Cox's模型研究根治性贲门癌的长期生存因素

Survival Factors in Patients with the Carcinoma of the Cadical Gastric Cardia by Cox's Proportional Hazard Model

目的 :研究影响贲门癌的预后因素。方法 :对 15 8例贲门癌根治术后患者作随访调查 ,应用统计软件对影响其术后的 16项可能因素作如下分析 :(1)单因素分析 Kruskal- wallis检验 ;(2 ) Cox's模型的多因素分析。结果 :确定了淋巴结转移总数、浸润深度、年龄、组织学分型为贲门癌根治术后的预后因子。结论 :根据 Cox's模型筛选的影响贲门癌预后的因子 ,帮助临床医师选择合理治疗方案 。

tic factors of influencing survival after resection of radical gastric cardia cancer. Methods:Follow up study was taken among 158 patients with radical carcinoma of the gastric cardia from January 1,1979 to January 1,1997.Sixteen prognostic factors were analyzed:(1)Unvariate analysis:Kruskal Wallis test for Kaplan Meier survival curve;(2)Multivariate analysis:Cox's proportional hazard model. Results:Four factors,the lymph nodes metastases numbers,the depth of invasion,ages,histologic differentiation,were proved to be relative with the prognosis of carcinoma of gastric cardia. Conclusion:The estimated model tallied with actual situation.