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低血糖生成指数膳食对妊娠期高血糖患者糖代谢情况的影响 被引量:3

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摘要 目的研究低血糖生成指数(LoGI)膳食对妊娠期高血糖患者血糖控制的作用。方法选取妊娠期高血糖患者364例,经口服葡萄糖耐量试验(0cTT)确诊为妊娠期糖尿病(GDM)或妊娠期糖耐量受损(GIGT),将所有患者按照完全随机化分组的原则分为对照组180例(给予正常膳食)和观察组184例(给予LoGI膳食),观察6周,所有患者采用自我血糖监测(sMBG)法记录治疗6周内糖代谢情况,6周后再行75gOGTr,测量两组患者血糖水平并比较。结果治疗0周时,两组75gOGTY空腹血糖和2h血糖比较差异无统计学意义(P〉0.05)。治疗6周时,75gOGTr空腹血糖对照组为(6.7±0.6)mmol/L,观察组为(5.7±0.5)mmol/L,两组比较差异有统计学意义(P〈0.05);2h血糖对照组为(9.3±0.7)mmol/L,观察组为(8.1±0.9)mmol/L,两组比较差异有统计学意义(P〈0.05)。观察组治疗2、4、6周时空腹血糖和餐后血糖显著低于对照组[空腹血糖:(5.5±0.6)mmol/L比(6.5±0.8)mmol/L、(5.3±0.7)mmol/L比(6.3±0.6)mmol/L、(5.2±0.6)mmol/L比(6.7±0.8)mmo]/L;餐后血糖:(8.0±0.7)mmol/L比(8.9±0.9)mmol/L、(7.7±0.9)mm01/L比(9.1±0.7)mmol/L、(7.8±0.8)mmol/L比(8.9±0.9)mmol/L],差异有统计学意义(P〈0.05)。治疗6周后观察组115例GDM患者中42例(36.5%)转为GIGT,50例(43.5%)转为糖耐量正常(NGT),对照组133例GDM患者中69例(51.9%)转为GIGT,12例(9.0%)转为NGT。观察期间两组患者体重增长值比较差异无统计学意义(P〉0.05)。结论LoGI膳食能有效调节妊娠期高血糖患者的血糖水平,可在临床推广应用。
作者 杨晓琴
出处 《中国医师进修杂志》 2012年第34期52-54,共3页 Chinese Journal of Postgraduates of Medicine
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参考文献12

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