期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

光学相干断层扫描技术在阿尔茨海默病诊断中的应用基础及进展

原文传递
导出
摘要 阿尔茨海默病（AD）是以进行性认知功能障碍和行为损害为特征的一种中枢神经系统退行性疾病，是老年期痴呆中最常见的类型，约占50％。随着年龄的增长，AD的患病率逐渐上升。AD的“治愈”仍是没有攻克的难关，其治疗也只是停留在“控制进展”的阶段，最重要的是现有药物也多半是早期使用效果较好，对于中晚期AD的治疗则收效甚微。鉴于此，
作者 郜丽妍 柏全豪 刘萍
机构地区 大连市友谊医院神经内科 大连市友谊医院眼科
出处 《中国医师进修杂志》 2012年第34期70-72,共3页 Chinese Journal of Postgraduates of Medicine
关键词 阿尔茨海默病 光学相干断层扫描技术 中枢神经系统退行性疾病 应用 诊断 认知功能障碍 老年期痴呆 控制进展
分类号 R749.1 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献23

  • 1Forlenza OV, Diniz BS, Gattaz WF. Diagnosis and biomarkers of predementia in Alzheimer's disease. BMC Med, 2010, $ : 89.
  • 2Ohno-Matsui K. Parallel findings in age-related macular degeneration and Alzheimer's disease. Prog Retin Eye Res,2011,30 (4):217- 238.
  • 3Cordeiro MF, Guo L, Coxon KM, et al. Imaging multiple phases of neurodegeneration: a novel approach to assessing cell death in vivo. Cell Death Dis,2010,1 :e3.
  • 4Koronyo-Hamaoui M, Koronyo Y, Ljubimov AV,et al. Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model. Neuroimage,2011,54 Suppl 1 :$204-217.
  • 5McKee AC, Au R, Cabral HJ,et al. Visual association pathology in preclinical Alzheimer disease. J Neuropathol Exp Neurol, 2006,65 (6) :621-630.
  • 6Armstrong RA. Visual field defects in Alzheimer's disease patients may reflect differential pathology in the primary visual cortex. Optom Vis Sci, 1996,73 ( 11 ) : 677-682.
  • 7Baloyannis SJ. Dendritic pathology in Alzheimer's disease. J Neurol Sci, 2009,283 (1/2) : 153-157.
  • 8Kirbas S, Turkyilmaz K, Anlar O, et 81. Retinal Nerve Fiber Layer Thickness in Patients With Alzheimer Disease. J Neuroophthalmol, 2012,32(4) : 1--4.
  • 9Kesler A, Vakhapova V, Korczyn AD, et al. Retinal thickness in patients with mild cognitive impairment and Alzheimer's disease. Clin Neurol Neurosurg, 2011,13 (7) : 523-526.
  • 10Marziani E, Ramolfo P, Mariani C, et al. Evaluation of retinal nerve fiber layer and ganglion layer cells thickness as biologic marker of Alzheimer's disease. Invest Ophthalmol Vis Sci, 2009,50:1096.

二级参考文献35

  • 1Hutton JT,Morris JL,Elias JW,et al.Contrast sensitivity dysfunction in Alzheimer's disease[J].Neurology,1993,43(11):2328-2330.
  • 2Gilmore GC,Wenk HE,Naylor LA,et al.Motion perception and Alzheimer's disease[J].J Gerontol,1994,49(2):P52-P57.
  • 3Cronin-Golomb A.Vision in Alzheimer's disease[J].Gerontologist,1995,35(3):370-376.
  • 4Blanks JC,Torigoe Y,Hinton DR,et al.Retinal pathology in ALzheimer's disease.I.Ganglion cell loss in foveal/ parafoveal retina[J].Neurobiol Aging,1996,17(3):377-384.
  • 5Hinton DR,Sadun AA,Blanks JC,et al.Optic-nerve degeneration in Alzheimer's disease[J].N Engl J Med,1986,315(8):485-487.
  • 6Hedges TR 3rd,Perez Galves R,Speigelman D,et al.Retinal nerve fiber layer abnormalities in Alzheimer's disease[J].Acta Ophthalmol Scand,1996,74(3):271-275.
  • 7Armstrong RA.Visual field defects in Alzheimer's disease patients may reflect differential pathology in the primary visual cortex[J].Optom Vis Sci,1996,73(11):677-682.
  • 8Sadun AA,Bassi CJ.Optic nerve damage in Alzheimer's disease[J].Ophthalmology,1990,97(I):9-17.
  • 9Iseri PK,Ahinas O,Tokay T,et al.Relationship between cognitive impairment and retinal morphological and visual functional abnormalities in Alzheimer disease[J].J Neuroophthalmol,2006,26(1):18-24.
  • 10Granholm E,Morris S,Galasko D,et al.Tropicamide effects on pupil size and pupillary light reflexes in Alzheimer's and Parkinson's disease[J].Int J Psychophysiol,2003,47(2):95-115.

共引文献11

中国医师进修杂志
2012年 第34期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部