多药耐药菌肺感染危险因素分析及对策

Analysis on risk factors of multiple drug - resistant bacteria lung infection and coun- termeasure

目的分析我院普外科2011年1～12月161例多药耐药菌感染患者的感染部位及28例发生多药耐药菌肺感染患者的情况，探讨其危险因素及预防处理措施，以减少多药耐药菌肺感染的发生。方法分析所有患者的临床资料，总结减少感染的对策。结果多药耐药菌肺感染的危险因素中，胃置定管、伴有基础疾病、使用二联以上抗菌药物所占比例分别为94．1％，78．6％，64．3％；28例多药耐药菌肺感染患者菌种构成中以ESBLs＋KPN和ESBLs＋ECO例数最多，为9例，比例为32．1％；其次为多药耐药ABA和MRSA，比例为25．0％和10．8％；感染部位以呼吸道感染为主，比例为41．0％，皮肤软组织、切口、血液、泌尿道所占比例分别为24．8％、15．5％、10．6％、8．1％。结论做好对多药耐药菌肺感染危险因素的防护，根据菌种检测结果合理用药，可以减少多药耐药菌肺感染的发生。

Objective To analyze surgery＇s infection positions of 128 patients with multiple drug -resistant bacteria lung infection from January 2011 to December 2011 in our hospital, and discuss the risk factors that induced the infection and the prevention treatment measures, in order to reduce the occurrence of infection. Methods The clinical data of all patients were analyzed and summarized the countermeasures of reducing infection. Results All the risk factors of multiple drug - resistant bacteria lung infection, the proportions of placed tube in stomach, basic diseases, use of duplex antibacterial drugs were respectively 94. 1% , 78.6% , 64. 3% ; the strains that infected the number of the patients most were mainly ESBLs KPN and ESBLs CON, followed by ABA and MRSA; the infection position was mainly re- spiratory tract, the proportion was 41.0% ; the proportions of skin soft tissue, notch, blood, urinary tract were 24. 8% , 15.5% , 10. 6% , 8.1% respectively. Conclusions We should make effects to protect the risk factors of the multiple drug - resistant bacteria lung infection, use drugs reasonable according to strains test results, reduce the occurrence of drug - resistant bacteria lung infection.