无精子症患者睾丸内精子存在的评估

Predictive factors for successful sperm recovery in azoospermia patients

目的 检测无精子症患者睾丸内精子存在情况。 方法 睾丸活检病例 5 0例 ,每例均作血内分泌激素检测、睾丸体积测量、睾丸组织学检查及睾丸精子提取 (TESE) ,分析促卵泡生成素(FSH)、睾丸体积和睾丸组织学与睾丸内精子存在的相关性。 结果 血FSH和睾丸体积预测睾丸精子是否存在准确性不强 ,而睾丸组织学结果与TESE一致 (敏感性 96 % ,特异性 10 0 % ,准确性10 0 % )。 结论 血FSH高和睾丸体积小的无精子症患者 ,应行睾丸活检并同时行TESE以明确睾丸内是否有精子。

Objective[WT5”BZ] To find any predictive factors for successful testicular sperm recovery in azoospermic patients. [WT5”HZ]Methods[WT5”BZ] 50 cases of azoospermia were subjected to testicular biopsy. Serum follicle stimulating hormone (FSH), concentration, testicular volume, testicular histopathology, and testicular sperm extraction(TESE)were determined in each cases. [WT5”HZ]Results[WT5”BZ] Neither serum FSH values nor testicular volume were predictive of spermatozoa in TESE. Testicular histopathology was specific for predicting successful sperm recovery (sensitivity 96%; specficity 100%; accuracy 100%). [WT5”HZ]Conclusions[WT5”BZ] Azoospermia patients with high FSH and small testis should be recommended for testicular biopsy and TESE to confirm if there is any testicular spermatozoa. [WT5”HZ]