透析液钠离子浓度个体化的临床应用观察

Clinical Application Observation of Individualized Sodium Concentration Dialysate

目的探讨根据透析液钠离子浓度个体化进行维持性血液透析治疗对患者临床指证及不良反应的影响。方法随机选取我院维持性血液透析治疗的患者78例,采用自身对照研究方法,前8个月给予常规血液透析治疗,后8个月根据患者病情选择透析液钠离子浓度,观察两个阶段治疗后患者临床指标和不良反应发生情况。结果经第二阶段治疗后,患者血清尿素氮(BUN)、高血压与低血压的发生率和低血糖的发生率均明显下降,与第一阶段比较具有统计学差异(P<0.05)。结论透析液钠离子浓度个体化可有效改善患者病情,减少透析不良反应。

Objective To explore the influence of individualized sodium concentration dialysate on the incidence of common clinical indices and adverse reactions. Methods 78 patients with maintenance hemodialysis treatment were selected and offered an 8-week regular hemodialysis, and then were given an 8-week hemodialysis with individualized sodium concentration at the second stage. The clinical indices and adverse reactions were compared between the two stages. Results The rate of BUN, hypertension, hypotension and hypoglycemia were distinctly lower （P 〈0.05） after the second stage treatment. Conclusions Individualized sodium concentration dialysis can effectively im prove the patient＇s condition and reduce the incidence rate of adverse reactions among maintenance hemodialysis patients.