硝酸甘油治疗高血压病合并稳定型心绞痛的分析

Clinical Research of Nitroglycerin in the Treatment of Hypertensive Patients with Stable Angina Pectoris

目的探讨硝酸甘油治疗高血压病合并稳定型心绞痛的临床疗效。方法硝酸甘油治疗高血压病合并稳定型心绞痛96例患者,随机分为观察组和对照组各48例,均给予常规治疗。观察组予硝酸甘油30mg微泵入,对照组予生理盐水微泵入,根据血压及心绞痛症状体征等变化,作为调整泵入速度。观察两组在缓解症状及体征的变化。结果观察组临床的显效率为66.67%,总有效率为93.75%;对照组临床的显效率为37.50%,总有效率为70.83%;显效率和总有效率的差异具有统计学意义(P<0.01)。结论硝酸甘油治疗高血压病合并稳定型心绞痛起效显著,临床疗效好。

Objective To investigate the clinical efficacy of nitroglycerin in treating hypertensive patients with stable angina pectoris. Methods 96 cases of hypertensive patients with angina pectoris were randomly divided into the treatment group and the control group. Both groups received conventional treatment. The patients in the treatment group got 30 mg of nitroglycerin through micro-pump, the patients in the control group got normal saline through micro-pump, and the speed was adjusted according to the changes in blood pressure, angina symptoms and signs. The changes of relieving signs and symptoms were observed between the two groups, Results The clinical effective rate of the treatment group was 66.67%, with a total effective rate of 93.75%; and the clinical effective rate of the control group was 37.50%, with a total effective rate of 70.83%. The effective rate and total effective rate between the two groups had statistically significant difference （P〈0.01）. Conclusions Nitroglycerin has significant clinical efficacy in treating hypertensive patients with stable angina pectoris.