氨溴索治疗慢性喘息性支气管炎急性发作55例观察

The Effect of Mucosolvan in the Treatment of 55 Patients with Acute Exacerbation of Chronic Asthmatic Bronchitis

目的:观察氨溴索雾化吸入治疗慢性喘息性支气管炎急性发作的临床疗效。方法:将110例慢性喘息性支气管炎急性发作患者随机分为观察组和对照组,每组各55例。对照组常规应用吸氧、抗生素、祛痰药和解痉平喘药等治疗。观察组在对照组治疗的基础上给予氨溴索15 mg加于生理盐水10 mL行氧驱动雾化吸入,bid,连续7 d。观察患者咳嗽、咯痰、喘息及肺部哮鸣等症状改善情况。结果:观察组总有效率为94.5%,对照组总有效率为69.1%,2组患者总有效率比较有显著性差异(P<0.05)。结论:氨溴索雾化吸入治疗慢性喘息性支气管炎急性发作疗效确切,值得临床推广应用。

Objective： To observe the effect of ambroxol atomization inhalation in treatment of acute exacerbation of chronic asthmatic bronchitis. Method： 110 patients with acute episode of chronic asthmatic bronchitis were randomly divided into Observation Group and the control group. 55 patients in observation group, 55 patients in the control group. The two groups had same treatment of oxygen, antibiotics and expectorant drug and reconciliation muscular spasm and asthma . Observation group had ambroxol 15 mg 10 mL joined in saline lines of oxygen driving atomization inhalation, tid for 7 d. Observed the cough, expectoration, and wheezing symptoms, and improving the situation of the lungs of patients in the course of treatment. Results：The total effective rate was 94.5% in observation group, the total effective rate of 69.1% in the control group, there were difference statistically significantly （P 〈 0.05 ） between the two groups. Conclusion： The effect of ambroxol atomization inhalation in treatment of acute exacerbation of chronic asthmatic bronchitis is certain, and is worth clinical application.