期刊文献+

冠心病辨证分型与Hs-CRP、HCY及LP(a)的相关性研究 被引量:9

下载PDF
导出
摘要 目的探讨冠心病中医辨证分型与炎症介质超敏C反应蛋白(Hs-CRP)、同型半胱氨酸(HCY)和脂蛋白(a)[LP(a)]的相关性。方法 162例冠心病患者予以辨证分型及Hs-CRP,HCY,LP(a)水平测定,并进行统计。结果冠心病组血清Hs-CRP,HCY,LP(a)水平与正常对照组比较有显著性差异(P<0.01),冠心病各中医证型之间血清Hs-CRP,HCY,LP(a)水平也有显著性差异(P<0.01),其中心血瘀阻,痰浊内阻两证型血清Hs-CRP,HCY,LP(a)水平均高于其它四个证型(均P<0.01)。结论 Hs-CRP,HCY,LP(a)是冠心病的独立危险因素,可作为冠心病中医辨证尤其是辨虚实及病情评估的重要指标。
作者 宋娅萍 刘青
出处 《光明中医》 2012年第8期1569-1572,共4页 GUANGMING JOURNAL OF CHINESE MEDICINE
  • 相关文献

参考文献12

  • 1Ridker PM, Rifai N, Pfeffer MA, et al. Inflammation, pravastatin, and the risk of coronary events after myocardial infarction in patients with areeage cholesterol levels. Cholesterol and Recurrert Events (CARE) Investigators[J]. Circulation,1998,98:839-844.
  • 2Rifai N, Tracy RP, Rikder PM. Clinical efficacy of art autornated high sensitivity C-reactive protein assay [ J]. Clin C hem, 1999,45: 2136-2141.
  • 3Pepys M, H irsch field G. C-reactive protein:a critical update Clin Invest,2003,111:1805-1812.
  • 4Calabro P,W illerson JT, Yeh ET. Inflammatory cytokines stimulate C-reactive protein prodution by human an coronary artery smooth muscle cells Circulation,2003,108 : 1930-1932.
  • 5Boushey C J, Beresford SA , Omenn GS , et al. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes [ J ]. JAMA, 1995,274 ( 13 ) : 1049-1057.
  • 6Bennet A, Di Angelantonio E. Erqou S, et al. Lipoprotein (a) levels and risk of future coronary heart disease : Large scale prospective data [ J ]. Arch Intern Med,2008,168 (6) : 598..608.
  • 7Zacho J, Tybjaery-Hansen A, Jensen J S , et al, C-reactive protein and risk of ischaemic vascular and cerebrovascular disease-secondary publication [ J]. U geskr Leager ,2009,171 (21) : 1751-1755.
  • 8Roy D,Quiles J,Avanzas P,et al. A comparative study of markers of inflammation for the assessment of cardiovascular risk in patients presenting to the emergency department with acute chest pain suggestive of acute coronay syndrome [ J]. Int J Cardiol, 2006,109: 317-321.
  • 9Faria-Neto JR, Chagas AC, Bydlowski SP. et al. l-Iyperhomocy stinenia in patients with coronary artery ehisease[ JJ. Braz J Med Bio Res,2006,39:455-463.
  • 10Stubbs PJ, Al-Obaidi MK, Conroy RM, et al. Effect of plasma homocysteine concentration on early and late events in patients with acute coronary syndromes [ J ]. Circulation,2000,102 : 605-610.

同被引文献191

引证文献9

二级引证文献30

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部