地佐辛复合丙泊酚静脉全麻用于宫腔镜手术的临床观察

Clinical observation on propofol combined with dezoeine intravenous general anesthesia in hysteroscopes operation

目的观察地佐辛复合丙泊酚静脉全麻对宫腔镜手术麻醉及术后镇痛的影响。方法择期行宫腔镜术患者80例随机分为地佐辛复合丙泊酚组（B组）和单纯丙泊酚组（P组），B组患者地佐辛0．1mg／kg＋丙泊酚2mg／kg，P组丙泊酚2mg／kg＋生理盐水1ml。记录麻醉前、麻醉后5min、扩宫颈时、停药后10min的舒张压（DBP）、收缩压（SBP）、心率（HR）、脉搏氧饱和度（SPO2），并记录手术时间、苏醒时间、丙泊酚总用量以及麻醉效果、眩晕发生率和术毕30min腹痛VAS评分。结果两组患者麻醉后5min的DBP、SBP均低于麻醉前（P〈0．05），停药后10min均恢复至术前水平；B组丙泊酚总用量显著低于P组[058．8±12．7）mgvs（210．0±22．3）mg]（P〈0．05），术中麻醉效果优于P组（p〈0．05），术毕30min疼痛VAS评分显著低于P组[（2．7±1．4）vs（6．4±2．1）]（P〈0．05）。结论地佐辛复合丙泊酚静脉全麻效果可靠，苏醒迅速，术后镇痛效果好，是一种安全有效的官腔镜术麻醉方法。

Objective To evaluate the effects of propofol combined with dezocine intravenous anesthesia and postoperative analgesia in hysteroscopes operation. Methods 80 cases of hysteroscopes were randomly divided into two groups： dezocine combined with propofol group （group B, dezocine 0.1 rag/ kg ＋ propofol 2 mg/kg） and propofol group （group P, propofol 2 mg/kg physiological saline lml）. DBP, SBP, HR and SPO2 of the patients at before induction, 5 min after induction, cervical dilatation and 10 min after operation were recorded. The operating time, anesthetic recovery, propofol dosage, quality of anesthesia, rate of dizziness and visual analog scale （VAS） of 30 rain after operation were also recorded. Results DBP and SBP at 5 min after induction in two groups were significantly lower than those before operation （P〈 0.05）. The dosage of propofol of group B was significantly less than that of group P [（158.8 ±12.7）rag vs（210.0±22.3） mg] （P〈 0.05）, anesthetic quality of group B was significantly higher than that of group P （P〈 0.05）, VAS score point of group B was significantly lower than that of group P [（2.7 ± 1.4） vs （6.4 ± 2.1）] （P〈 0.05）. Conclusion Intravenous anesthisa by using propofol combined with dezocine in hysteroscopes can guarantee the anesthetic quality with quick recovery from anesthesia and decrease the intensity of postoperative pain, which can be safely used in hysteroscopes.