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碘催化亚胺与烯醇醚的新反应研究

Study on the New Reaction of Imine with Enol Ethers Catalyzed by Iodine
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摘要 研究了在碘催化下亚胺与烯醇醚的反应,以较高的产率获得了预期的四氢喹啉产物。详细考察了催化剂的用量、亚胺的结构以及烯醇醚的结构对这一反应的影响。所得化合物经1 H NMR、13C NMR测试技术进行表征。 Iodine was found to be an efficient catalyst for the reaction of imin with enol ethers to provide tetrahydroquinolines in good yields.The influence of the loading of iodine and the structure of imine and enol ethers was studied.In addition,the obtained compounds were characterized by 1H NMR、13C NMR.
作者 惠飞 赵伟杰
出处 《化学世界》 CAS CSCD 北大核心 2012年第12期750-752,共3页 Chemical World
基金 河南省重点科技攻关项目(112102210382)
关键词 亚胺 烯醇醚 四氢喹啉 iodine imine enol ethers tetrahydroquinoline
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参考文献8

  • 1CROMWELL N H, MOHRBACHER R J. Ethyleni- mine Ketones. X. The Stereoisomerism of 1-Cyelohex- yl-2-methyl-3-(p-phenylbenzoyl)-ethylenimine[J]. J Am Chem Soc, 1953, 75: 6252.
  • 2RAMALINGA K, VIJAYALAKSHMI P, KAIMAI T N B. A Mild and Efficient Method for Esterification and Transesterification Catalyzed by Iodine [J]. TetrahedronLett. 2002, 43: 879.
  • 3SUN J W, DONG Y M, CAO L Y etal. Highly Effi- cient Chemoselective Deprotection of O,O-Acetals and O,O-Ketals Catalyzed by Molecular Iodine in Acetone [J]. J Org Chem, 2004, 69.. 8932.
  • 4PHUKAN P. Iodine as a Very Powerful Catalyst for Three-Component Synthesis o{ Protected Homoallylic Amines[J]. J Org Chem, 2004, 69: 4005.
  • 5JOHNSON J V, RAUCKMAN S, BACCANARI P D, et al. 2,4-Diamino-5-benzylPyrimi-dines and Ana- logues as Antibacterial Agents.. Analogues with High Activity and Specificity for Bacterial Dihydrofolate Re- ductase[J]. J Med Chem, 1989, 32: 1942,2-1945.
  • 6CARLING R W, LEESON P D, MOSELEY A M, et al. 2-Carboxytetrahydroquinolines. Conformational and Stereochemical Requirements for Antagonism of the Glycine Site on the NMDA Receptor[J]. J Med Chem, 1992, 35: 1942-1946.
  • 7YAMADA N, KADOWAKI S, TAKAHASHI K, et al. MY-1250, A Major Metabolite of the Anti-allergic Drug Repirinast, Induces Phosphorylation of a 78-kDa Protein in Rat Mast Cells[J]. Bioehem Pharmaeal, 1992, 44, 1211-1214.
  • 8BOWMAN R K, JOHNSON J S. Assembly of Cyclo- palladated Units: Synthesis, Charaeterisation, X-Ray Crystal Structure and Study of the Reactivity of the Tetramet-allic Cyclopalladated Complex [- Pd {C6H4CHN (C6H4 2-O)}]4 · 2CHC13 [J]. J Org Chem, 2004, 69.- 8537-8540.

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