不动杆菌感染及耐药性的研究

Study on infection and resistance of acinetobacter calcoaceticus

目的 了解不动杆菌院内感染现状 ,研究其耐药机制 ,为制定预防和控制其院内感染措施提供依据。方法 对我院不动杆菌的感染进行调查 ,采用药敏试验、质粒抽提和限制性核酸内切酶分析法、质粒消除试验。结果 不动杆菌在我院病房检出率为 0～ 18.2 4% ,以烧伤病房检出率最高。结论 各病房有特定的流行株 ,不同质粒编码不同耐药性。

Objective To investigate infection and resistance of acinetobacter calcoaceticus in our hospital and take out measure to control nosocomial infection.Methods Isolates were identified as acinetobacter calcoaceticus by using antibiotic susceptibility test,plasmid profiles,restriction enzyme fingerprinting assay and plasmid elimination method.Results The isolation rate was 0 to 18 24% in our hospital wards.The isolation rate in burn ward was higher than that in any other ward. Conclusion Each ward has its special isolates,Different plasmid mediated different resistance patterns.