广州地区淋球菌血清学和营养分型研究

Study on Serotypes and Auxotypes of Neisseria Gonorrhoeae in Guangzhou

目的 确定广州地区淋球菌血清型和营养型流行特点。方法 采用乳胶凝集法对 131株淋球菌进行血清学分型和 La Scolea法分析 108株淋球菌营养型。结果 血清学分型以 WⅡ /WⅢ为主，占 87.8％ (115/131), WⅠ 型仅为 9.9％ (13/131)；营养型则以 Proto、 Proˉ和 ILeˉ 3种营养型为主，分别占 42.6％、 21.3％和 12.0％；另外 WⅠ 仅见于 Proto和 Proˉ营养型， WⅡ /WⅢ可见于所有营养型。结论 血清型 WⅡ /WⅢ的优势群和营养型中 ILeˉ型明显高于其它省份是广州地区淋球菌流行的两大特点。

Objective To investigate the serotype and auxotype distributions of Neisseria gonorrhoeae in Guangzhou.Method One hundred and thirty one strains of Neisseria gonorrhoeae were serotyped by co－ agglutination test and 108 strains were auxotyped by La Scolea′ s method.Results Out of 131 strains of Neisseria gonorrhoeae, 87.8％ (115/131) wereWⅡ /WⅢ , while 9.9％ (13/131) were WI. The predominant auxotypes were Proto, Proˉ and ILeˉ , accounting for 42.6％ (46/108), 21.3％ (23/108) and 12.0％ ,respectively. WⅡ /WⅢ was found in all auxotypes whereas WI only in Proto and Proˉ auxotypes.Conclusion The study illustrates the prevailing serotype of WⅡ /WⅢ , and the prevalence of ILeˉ in Guangzhou.