进展性脑梗死的相关因素分析

Analysis of correlated factors of progressive cerebral infarction

目的探讨进展性脑梗死的相关因素。方法回顾性分析进展性脑梗死的临床资料,观察其既往史、体温、血压、血糖、血脂、纤维蛋白原、感染及动脉狭窄程度,并与同期非进展性脑梗死42例患者进行比较。结果进展组患者糖尿病史、高血压史、短暂性脑缺血发作(TIA)史明显高于非进展组(P<0.05);进展组收缩压明显低于非进展组;空腹血糖、纤维蛋白原水平明显高于非进展组(P<0.05));进展组感染的发病率明显高于非进展组(P<0.05);进展组颈内动脉中、重度狭窄患者明显多于非进展组。结论高血压、糖尿病、TIA发作史、感染、颈内动脉狭窄是脑梗死进展的危险因素,当患者收缩压降低、脉压减小时应引起高度重视。

Objective To discuss the correlated factors of progressive cerebral infarctions.Methods Retrospective analysis was made on previous history,body temperature,blood pressure,blood glucose,blood lipids,fibrinogen,infection history and the stenosis of the internal carotid arteries in 40 progressive cerebral infarction patients（progressive group） and the results were compared with 42 non-progressive cerebral infarction patients（non-progressive group）at the same period.Results The history of diabetes,hypertension and transient ischemic attack were significantly higher in progressive group than that in non-progressive group（P〈0.05）;the systolic pressure was significantly lower in progressive group than that in non-progressive group;the level of fasting blood glucose and fibrinogen were significantly higher in progressive group than that in non-progressive group（P〈0.05）;the incidence of infection was significantly higher in progressive group than that in non-progressive group;Far more patients with moderate to sever stenosis of internal carotid arteries were seen in progressive group than that in non-progressive group.Conclusion Hypertension,diabetes,history of transient ischemic attack,infection and stenosis of internal carotid arteries are risk factors of progressive cerebral infarction,and special attention should be taken when the patient＇s systolic pressure dropping,narrowing the pulse pressure.