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前降钙素原对脓毒症早期诊断和分级的意义

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摘要 目的探讨前降钙素原(Procalcitonin,PCT)对脓毒症的早期诊断和分级的意义。方法选取2011年5月~2012年3月入住急诊科的62例患者,其中脓毒症44例(其中严重脓毒症患者19例,一般脓毒症患者25例),非脓毒症的全身炎症(systemic inflammatory response syndrome,SIRS)反应患者18例;同期健康对照组21例。抽取静脉血2ml,采用免疫荧光法测定PCT。结果脓毒症组血清PCT浓度(6.34±5.75)μg/L高于SIRS组(0.64±0.11)μg/L和对照组(0.50±0.03)μg/L,严重脓毒症组血清PCT浓度(10.67±6.65)μg/L高于一般脓毒症组(3.06±0.10)μg/L,SIRS组血清PCT浓度和对照组差异无统计学意义。结论 PCT可以鉴别脓毒症和SIRS,并且PCT与脓毒症的严重程度正相关。PCT可以作为脓毒症诊断和分级的标志物。
出处 《湘南学院学报(医学版)》 2012年第4期42-43,共2页 Journal of Xiangnan University(Medical Sciences)
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