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急性心肌梗死直接PTCA后心电图变化与临床预后的关系

The relation between the change of elect rocardiogram and clinical outcome after primary angioplasty in patients with ac u
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摘要 目的 :探讨直接经皮冠状动脉腔内球囊成形术 (PTCA)治疗急性心肌梗死(AMI)后心电图抬高的ST段的变化与临床预后的关系。方法 :10 8例成功行直接PTCA的AMI患者 ,分析术后 1h 12导联心电图抬高的ST段下移幅度 ,分为四组 :A组 :抬高ST段下移 10 0 % ;B组 :抬高ST段下移 5 0 %~ 10 0 % ;C组 :抬高ST段下移 0~ 5 0 % ;D组 :ST段无下移。结果 :四组梗死相关血管 (IRA)开通时间相似 ,A组患者下壁和 /或后壁、右室梗死占 84 6 % ,与其余三组比较均有显著性差异 (P <0 0 1~ 0 0 5 )。抬高ST段下降≥ 5 0 %组比 <5 0 %组的CPK、CK-MB峰值 ,梗死延展发生率及病死率明显下降 (分别为 32 6 6 1± 2 15 7 6比 436 4 0± 2 873 0 ,134 5± 80 1比 176 9± 10 7 5 ,0比 6 1% ,1 3%比 12 1% ,P <0 0 5 ) ,LVEF明显升高 (5 8 5±12 9比 5 1 5± 16 0 ,P <0 0 5 )。结论 :AMI成功再灌流治疗后抬高ST段下移幅度可作为判断预后的一个重要指标 ,迅速下降≥ 5 0 %组梗死面积小 ,左室收缩功能好 ,近期心脏事件发生率及病死率低。 To investigat e the change of ST-segment elevation in relati on to clinical outcome after primary cor o nary angioplasty in patients with acute myocardial infarction(AMI).Methods : A hundred and eight c onsecutive patients with AMI underwent s uccessful primary angioplasty.The extent of the ST-segment elevation resolution on electrocardiogram one hour after prim ary angioplasty was analysed. WTHZ Resu lts: WTBZ Th e four groups had similar time of restor ation of flow in the infarct-related art ery.Compared with patients with ST-semen t elevation re solution<50%,patients with ST-segment e levation resolution≥50% had lower peak C PK,CK-MB(3266 1±2157 6 vs 4364 0±2873 0,134 5±80 1 v s 176 9±107 5,P<0 05),and lower incidence of i nfarct extension,lower mortality and bet ter le ft ventricular ejection fraction(LVEF) ( 0 vs 6 1%,1 3% vs 12 1%,58 5±12 9 vs 51 5±16 0,P< 0 0 5). WTHZ Conclusion: WTBZ Patients who had received successful reperfusion therapy after AMI with rapid ST-segment elevation resolut ion≥50% had limited infarct size,better l eft ventricular function,lower cardiac e vent and mortality.
出处 《急诊医学》 CSCD 2000年第3期168-170,共3页
关键词 急性心肌梗塞 血管成形术 PTCA 心电图 Acute myocardial infarctionAngioplastyTransluminal percutaneous coronary Electrocardiogram
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参考文献5

  • 1Kenner M,Zajac EJ,Kondos GT,et al.Ability of the no-reflow phenomenon during an acute myocardial infarction to predict left vemricular dysfunction at one-monty follow-up.Am J Cardiol.1995.76:861.
  • 2Matetzky S,Freimark D,Chouraqui P,et al.The distiaction between coronary and myocardial reperfusion after thrombolytic therapy by clinfcal markera of reperfusion .J Am Coll Cardiol.1998.32:1326.
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