支原体感染与儿童哮喘急性发作关系的临床研究

Clinical analysis on the association between mycoplasma pneumoniae infection and bronchitic asthma attacking

目的:探讨肺炎支原体感染与儿童哮喘急性发作的关系。方法:收集支气管哮喘急性发作患儿61例(观察组)、上呼吸道感染患儿99例(对照组),采用被动凝集法检测血清肺炎支原体抗体lgM(MP-lgM)。结果:观察组患儿MP-lgM阳性率为50.8%,显著高于对照组的35.4%,差异有统计学意义(P<0.05)。观察组A组平均住院时间为(7.29±1.51)d,显著高于对照组的(6.57±1.14)d,差异有统计学意义(P<0.05)。结论:肺炎支原体感染可能是引起儿童哮喘急性发作的重要病原之一,哮喘发作患儿常规检测MP-Ab十分必要。

Objective To explore the association between the mycoplasma pneumonia （MP） infection and bronchitic asthma attac- king. Method There were 61 patients with bronchitic asthma attacking taken as observation group ,and 99 cases with upper respiratory tract infection were taken as control group. MP - IgM of every case was detected by passive agglutination method. Results The MP positive rate of observation group （50. 8% ） was significantly higher than that of control group （35.4% ,P 〈 0. 05 ）. The average length of time in hospital of MP positive group （7.29 ± 1.51 d） was significantly higher than that of MP -IgM passive group （6. 57 ± 1.14, P 〈 0. 05 ）. Conclusion MP infection may play an important role in bronchitic asthma attacking and aggravating, and the detection of MP - Ab in the patients with asthma attacking was highly necessary.