肺结核空洞住院患者结核菌耐药性分析

Analysb of the tuberculosis drug-resistance characteristics of pulmonary tuberculosis with cavitary of hospitalized patients

目的:探讨肺结核空洞住院患者结核菌耐药性特征。方法:采用BACTEC MGIT快速培养仪做痰结核菌耐药性及药敏试验。结果:肺结核空洞患者总耐药率,耐单药率,耐多药率高于肺结核未出现空洞患者;耐药顺序从高到低依次为:异烟肼(H)、链霉素(S)、利福平(R)、乙胺丁醇(E)。结论:高耐药率,尤其是肺结核空洞患者高耐药率,应引起全社会的重视,寻找一条切实可行的控制耐药结核菌的办法是目前的当务之急。

Objective To investigate the tuberculosis drug - resistance characteristics of tuberculosis with cavitary of hospitalized pa- tients in our city. Method We used rapid culture system with BACTEC MGIT to do sputum drug resistance and sensitivity test. Results （ 1 ） The total resistance rate, single drug resistance rate and emergence of MDR - TB rates were higher in patients with pulmonary tubercu- losis cavity than in patients without cavity; （2） resistance order from high to low was：H, S, R, E. Conclusion High resistance rates of drug resistance tuberculosis,especially in patients with pulmonary tuberculosis cavity, should be payed a attention by the whole society. Looking for a practical way to control drug- resistant tuberculosis is a current priority.