用钳夹法制作心肌缺血再灌注损伤模型的研究

The Study of forceps operation on making reperfusion injury of ischemic myocardium model

目的 :了解用无创伤动脉夹钳夹冠状动脉制作心肌缺血再灌注损伤模型的效果。方法 :用无创伤动脉夹钳夹冠状动脉制作心肌缺血再灌注损伤模型 37例。结果 :此法的血流阻断的成功率及血管再通的成功率均是 10 0 % ,血管损伤并发症发生率占 5 .4% (2 /37)。结论 :钳夹法制作心肌缺血再灌注损伤模型的成功率及血管再通的成功率均为 10 0 %。而血管损伤并发症发生率低 ,钳夹法是一制作心肌缺血再灌注损伤模型的较好方法。

Objective:To investigate the effect of forceps operation on making reperfusion injury of ischemic myocardium model Methods:37 cases of reperfusion injury of ischemic myocardium model on mini pig were made with forceps operation Results:The rate of success on acute ischemic and reperfusion was all 100% But rate of blood vessel injure was 5 4%(2/37) Conclusion:Forceps operation is a good method in making reperfusion injury of ischemic myocardium model