交替使用尿素和平阳霉素注射治疗小儿大面积血管瘤的临床研究

Clinical study on alternate use of urea and bleomycin injections to treat children′s large-area heamangioma

本研究以注射用尿素和平阳霉素交替使用方法 ,经选择性动脉插管和瘤体局部注射 ,对 6 2例小儿各种类型不能切除的大面积血管瘤进行治疗 ,经 6个月～ 5年随访 6 0例 ,血管瘤消失或基本消失 5 6例 ,占 93.3%。两药交替使用 ,利用了两药各自优点 ,有加快血管瘤内皮细胞发生纤维性变作用 ,从而达到缩短疗程 ,用药量少 ,提高治疗效果 ,值得推广应用。

Objective:To treat children′s large area heamangioma,By alternate used urea and bleomycin and selective artery intubatton and local injections of tumour,62 cases of various large area heamangioma that can′t be ablated have been treated,After 6 months to 5 years,60 of which are followed up for 6 months to 5 years In 56 cases of 60 cases(93 3%) heamangioma has disappeared or nearly disappeared The results suggested that taking their own advantages can speed up the fibrilla action of the heamangioma endothelium,hence shotten the period of treatment and reduced the dose