南宁市足月新生儿胆红素动态观察

The bilirubine value of different period in normal term newborn in Nanning

目的 :了解本地足月新生儿黄疸的临床流行病学资料。方法 :同时测定 91例新生儿的经皮胆红素指数与血清总胆红素浓度值 ,求两者相关关系。用经皮胆红素仪测定 2 2 7例足月健康新生儿的生后 1～ 8天的经皮胆红素指数。结果 :经皮胆红素指数与血清总胆红素浓度值存在相关关系。 Y=0 .76 X+10 .6 (r=0 .918,t=2 1.89,P <0 .0 0 1)。黄疸在生后第 4～5天达最深 ,均值为 (180 .9± 45 .0 )μm ol/L (10 .6± 2 .6 mg/dl)。 2 2 .7%足月新生儿其总胆红素浓度大于 12 .9mg/dl,11.0 1%大于 15 mg/dl。结论 :根据统计学原则将本地区正常新生儿生后第 4～ 5天时的第 95个百分位数作为生理性黄疸的上限 ,当血清胆红素浓度值≥ 2 71.9μmol/L (15 .9m g/dl)为新生儿高胆红素血症的诊断标准。

Objective:To study the clinical epidemiology of jaundice in term healthy newborn of Nanning Method:The linear correlation between transcutaneous bilirubin index(TcBI) and total serum bilirubin(TSB) were studied in 91 jaundiced neonates The TcBI of 227 cases of healthy term newborn were measured at 1st to 8th days postnatally Results:There are good liner correlation between transcutaneous bilirubin index(TcBI) and total serum bilirubin(TSB) in 91 jaundiced neonates Y=0 76X+10 06(r=0 918,t=21 89,P<0 001) The bilirubine value is highest in 4th and 5th days after birth,the mean value was 180 9±45 0μmol/L In 22 7% of this group their bilirubin value is more than 220μmol/L 11 01% is more than 256 μmol/L Conclusions:We suggest that the criterion for neonatal hyperbilirubinemia would be 270μmol/L(15 9mg/dl) in Nanning