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英夫利西单抗治疗炎性肠病相关性关节炎1例报告 被引量:1

A case of infliximab treating inflammatory bowel disease related arthritis
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摘要 肿瘤坏死因子(TNF)-a在脊柱关节炎(SpA)和炎性肠病(IBD)的发病机制中占有重要的地位,阻断TNF生物合成或生物作用的抗TNF治疗已经成为SpA和IBD治疗的新方向。本文介绍了1例以关节肿痛起病的SpA患者在接受依那西普治疗的过程中出现IBD的临床表现,后换用英夫利西单抗即获得显著疗效的案例。现报道如下。
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2012年第12期971-972,I0009,共3页 Chinese Journal of Practical Internal Medicine
关键词 英夫利西单抗 脊柱关节炎 克罗恩病 炎性肠病相关性关节炎 Infliximab spondyroarthritis Crohn's disease inflammatory bowel disease related arthritis
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  • 1Rigby WF. Drug insight: differernt mechanisms of action of tumor necrosis factor antagonists passive aggressive behavior? [ J ]. Nat Clin Pract Rheumato1,2007,3 (4) :227 - 233.
  • 2Lugering A,Schmidt M,Ltigering N,et aL Infliximab induces apop- tosis in monocytes from patients with chronic active Crohn's disease by using a caspasedependentpathway [ J ]. Gastroenterology, 2001, 121 (5) :1145 - 1157.
  • 3Ten Hove T, van Montfrans C, Peppelenbosch MP, et al. 1 nfliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease [ J ]. Gut,2002,50 ( 2 ) : 206 - 211.
  • 4Burewer M, Luegering A, Kucharzik T, et al. Proinflammatory cyto- kines disurpt epithelial barrier function by apoptosis independent mechanisms[J]. J Immunol,2003 171 (ll) :6164 -6172.
  • 5Conti F, Ceecarelli F, Marocchi E, et al. Switching tumour necrosis factor alpha antagonists in patients with ankylosing spondylitis and psoriatic arthritis:an observational study over a 5-year period [ J ]. Ann Rheum Dis. 2007,66 (10) : 1393 - 1397.
  • 6Sands BE, Blank MA, Patel K, et al. Long-term treatment of rectova- gina fistulas in Crohn's disease response to infliximab in the AC- CENT lI Study [ J ]. Clin Gastroenterol Hepato1,2004,2 ( 10 ) :912 - 920.
  • 7Richter JA, Bickston SJ. Infliximab use in luminal Crohn's disease [ J ]. Gastrocnterol Clin North Am,2006,35 (4) :775 - 793.
  • 8Poupardin C, L mania M, Gendre JP, et al. Efficacy of infliximab in Crohn's disease. Results of a retrospective muhieenter study with a 15-month follow-up [ J ]. Gastroenterol Cli Biol,2006,30 ( 2 ) :24;7 - 252.
  • 9Hommes DW, Oldenburg B, Bodegraven van AA, et al. Guidelines for treatment with infliximab for Crohn's disease [ J]. Neth J Med, 2006,64(7) :219 -229.

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