期刊文献+

伐昔洛韦治疗复发性生殖器疱疹疗效观察 被引量:1

Curative effect observation of valaciclovir therapy in the treatment of recurrent genital herpes zoster
下载PDF
导出
摘要 目的评价伐昔洛韦治疗复发性生殖器疱疹的临床疗效。方法将入选患者随机分为2组,实验组患者给予伐昔洛韦,对照组给予阿昔洛韦,对2组患者复发情况进行观察。结果与对照组相比,伐昔洛韦能明显减少患者的疱疹复发次数,有效率高于对照组。结论伐昔洛韦能有效预防生殖器疱疹的复发。 Objective To evaluate the clinical curative effect of valaciclovir in the treatment of recurrent genital herpes. Methods The patients were randomly divided into 2 groups. The experiment group received valaciclovir while the control group received acyclovir. The recurrences of the two groups were observed. Results Compared with the control group, valacyclovir can significantly reduce the frequency of patients with recurrent herpes. The efficiency was higher than that in control group. Conclusion Valaciclovir is effective in preventing the recurrence of genital herpes.
作者 张建芬
出处 《实用临床医药杂志》 CAS 2012年第21期166-167,共2页 Journal of Clinical Medicine in Practice
关键词 生殖器疱疹 伐昔洛韦 疗效 genital herpes valaciclovir curative effect
  • 相关文献

参考文献3

  • 1生殖器疱疹临床诊疗指南(2009)[J].中华皮肤科杂志,2009,42(12):877-878. 被引量:45
  • 2Weller S,Blum M R,Doucette M,et al.Pharmacokineties ofthe acyclovir pro-drug valaciclovir after escalating single andmultiple-dose administration to normal volunteers[J].ClinPharmacol Ther,1993,54(6):595.
  • 3Williams J R,Jordan J C,Davis E A,et al.Suppressive vala-cyclovir therapy:impact on the population spread ofHSV-2 in-fection[J].Sex Transm Dis,2007,34(3):123.

共引文献44

同被引文献17

  • 1Nguyen S, Kennedy M, Gunawardana D,et al. Safety and pharmaco- kinetics of acicIovir in women following release from a silicone elasto- mer vaginal ring. The Journal of Antimicrobial Chemotherapy,2012, 67 (8) : 2005 -2012.
  • 2David I, Bernstein Rhonda D, Cardin Feruando J, et al. Topical SMIP - 7.7, a toll - like receptor 7 agonist, protects against genital herpes simplex virus type - 2 disease in the guinea pig model of geni- tal herpes. A ntiviral Chemistry & Chemotherapy ,2014,23 (5):189 - 196.
  • 3Laura Shepherd. Common themes and cognitive biases in the negative thoughts of women with recurrent genital herpes: clinical reflections and implications for cognitive behaviour therapy. Sexual and Relation- ship Therapy, 2010,25 (2) :148 -159.
  • 4Sita Awasthi, Jialing Huang, Carolyn Shaw,et al. Blocking herpes simplex virus 2 glycoprotein E immune evasion as an approach to en- hance efficacy of a trivalent subunit antigen vaccine for genital her- pes. J Virol,2014,88(15) : 8421 -8432.
  • 5Nicolas ~uburu, Kening Wang, Kyle N Goodman,et al. Topical her- pes simplex virus 2 ( HSV - 2 ) vaccination with human papillomavir- us vectors expressing gB/gD ectodomains induces genital - tissue - resident memory CD8 + T ceils and reduces genital disease and viral shedding afler HSV -2 challenge. J Virol,2015, 89( 1 ) : 83 -96.
  • 6Briana Nixon, Martha Stefanidou, Pedro MM Mesquita,et al. Grif- fithsin protects mice from genital herpes by preventing cell - to - cell spread. J Virol, 2013,87 ( 11 ) : 6257 - 6269.
  • 7Awasthi John W, Balliet Jessica A, Flynn John M, et al. Protection provided by a herpes simplex virus 2 ( HSV - 2) glycoprotein C and D subunit antigen vaccine against genital HSV -2 infection in HSV - 1 -seropositive guinea pigs. Journal of Virology,2014,88 (4) : 2000 - 2010.
  • 8唐云志,刘学军,刘劲松,等.大剂量伐昔洛韦长期抑制疗法治疗复发性生殖器疱疹疗效分析.中国医师杂志,2012,2(2):96—97.
  • 9Christine Johnston, Jia Zhu, Lichen Jing, et al. Virologic and immu- nologic evidence of muhifocal genital herpes simplex virus 2 infec- tion. J Viro1,2014,88 (9) : 4921 - 4931.
  • 10宋颖劼,吴原.伐昔洛韦长期与间歇抑制疗法预防生殖器疱疹复发疗效比较[J].浙江医学,2011,33(3):423-424. 被引量:2

二级引证文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部