保留肋间臂神经的乳腺癌改良根治术60例疗效观察

Observation on effect of 60 cases of modified radical mastectomy with preservation of intercostobrachial nerves

目的观察保留肋间臂神经的乳腺癌改良根治术的临床疗效。方法回顾性研究120例行乳腺癌改良根治术的患者,随机分为2组,每组60例,研究组术中保留肋间臂神经,对照组术中切除肋间臂神经,观察2组患者术后1个月、3个月、6个月的临床疗效以及不良反应。结果 2组患者手术时间、术中出血量、淋巴结数清扫数目无统计学差异。研究组患者术后出现轻微的上肢及腋部皮肤感觉异常,且感觉异常面积、并发症发生率也显著低于对照组。结论保留肋间臂神经的乳腺癌改良根治术可以避免上臂、腋窝等皮肤处感觉障碍的发生,显著改善患者术后生活质量、术后不良反应少,值得在临床推广使用。

Objective To observe the clinical effect of modified radical mastectomy with preservation of intercostobrachial nerves. Methods 120 patients underwent modified radical mastec- tomy were analyzed retrospectively and were randomly divided into 2 groups, 60 cases in each group. The intercostobrachial nerves were preserved in research group, while reseeted in control group. The clinical efficacy and adverse reaction in 1 month, 3 months, 6 months after operation were observed between 2 groups. Results Compared with the control group, the operation time, bleeding volume, number of lymph node dissection in research group had no statistical differences. Postoperative mild abnormalities in upper limb and axillary skin occurred in the research group, and the abnormal sensory area, the complication rate of research group were significantly lower than control group. Conclusion Modified radical masteetomy with preservation of the intercostobrachial nerves can avoid the occurrence of abnormal sensory and impairment in skins of upper and axillary. It also can significantly improve the postoperative quality of life and has less adverse reactions, so it is worthy of clinical application and popularization.