基于β-环糊精和二茂铁主客体作用的超分子聚合物的制备及其凝胶化

Preparation and Gelation of Supramolecular Copolymer Based on the Host-Guest Interaction between Cyclodextrin and Ferrocene

以β-环糊精修饰的壳聚糖(CDCS)和二茂铁修饰的聚乙二醇(FcPEG)为构筑单元,以β-环糊精和二茂铁的主客体相互作用为驱动,构筑了水溶性的超分子聚合物CDCS-FcPEG。在此基础上,加入α-环糊精(α-CD),通过其对聚乙二醇的穿环络合诱导结晶作用,制备了壳聚糖基水凝胶。使用核磁(1 H-NMR)、紫外-可见光谱法(UV-Vis)、X射线衍射分析(XRD)和循环伏安法(CV)等手段进行了验证。结果表明:超分子聚合物CDCS-FcPEG与共价键连接的传统聚合物一样可以和α-CD形成凝胶。

Driven by the host-guest interaction betweenβ-cyclodextrin and ferrocene in aqueous solution, a water-soluble supramolecular copolymer CDCS-FcPEG was obtained based on β-cyclodextrin modified chitosan （CDCS） and ferrocene modified polyethylene glycol （FcPEG） as building blocks. The CDCS- FcPEG further constructed into hydrogel with α-cyclodextrin （a-CD）, owing to the formation of crystalline inclusion complex of α-CD and PEG. These processes were monitored by 1 H-NMR, UV-Vis spectroscopy （UV-Vis）, X-ray diffraction （XRD） and cyclic voltammetry （CV）. Results show that CDCS-FcPEG can form hydrogel with a-CD like traditional copolymers linked by covalent bonds.