AMI患者CK-MB峰值与单核细胞相关性以及对患者预后的研究

Correlation Research of CK-MB Peak and Mononuclear Cell and Prognosis in AMI Patients

目的:探索急性心肌梗死(AMI)CK-MB峰值结果与外周血单核细胞值的关系,分析患者预后。方法:89例急性心肌梗死患者按预后情况分为两组,预后良好组54例和预后不良组35例,正常对照组67例,分别统计肌酸激酶同工酶峰值结果,同时测定外周血单核细胞的值,并比较各组肌酸激酶同工酶MB(CK-MB)值以及相关性。结果:患者单核细胞与CK-MB值存在着一定的相关性(r=0.73,P<0.05),预后良好组单核细胞结果为(0.60±0.23)×109/L、预后不良组为(1.19±0.59)×109/L,两组间比较差异有统计学意义(P<0.05)。而预后良好组CK-MB结果为(147.96±87.30)U/L,预后不良组为(286.33±145.76)U/L,两者比较差异有统计学意义(P<0.05)。结论:急性心肌梗死患者再通不良时CK-MB值峰值和单核细胞结果可以作为早期AMI患者病情预后的判断指标。

Objective：To explore the acute myocardial infarction （ AMI ） CK-MB peak results and peripheral blood mononuclear ceil value relations, the prognosis of patients with analysis.Method：89 cases of acute myocardial infarction patients according to the prognosis were divided into two groups, the prognosis was good group of 54 and poor prognosis group 35 examples, 67 cases of normal control group respectively, statistical creatine kinase isozyme peak results and simultaneous determination of peripheral blood mononuclear cell values, and compare the creatine kinase isozyme MB （ CK-MB ） value and correlation. Result：Patients mononuclear cells and CK-MB value exist certain correlation （ r=-0.73, P〈0.05 ）, the prognosis was good group of mononuclear cell results was （ 0.60 ±0.23 ） Х10^9/L, poor prognosis group of mononuclear cell results was （ 1.19±0.59 ）×10^9/L, comparison between the two groups had significant difference （ P〈0.05 ） .However prognosis was good group of CK-MB results （ 147.96±87.30 ） U/L and prognosis group CK-MB result was （ 286.33±145.76 ） U/L, which show a significant difference （ P〈0.05 ） .Conclusion：We think that acute myocardial infarction patients when recanalization bad CK-MB value peak and mononuclear