58例梅毒孕妇治疗因素与妊娠结局关系分析

Relationship of Treatment Factors and Pregnancy Outcome in 58 Cases of Syphilis in Pregnant Women

目的:探讨分析梅毒孕妇的治疗因素同妊娠结局的关系。方法:随机选取2009年12月-2011年12月本院诊疗随访的58例梅毒孕妇,妊娠期未实施全程抗梅毒治疗的作为对照组,共28例孕妇,妊娠期实施全程抗梅毒治疗的作为观察组,共30例孕妇,比较分析两组的妊娠结局及新生儿情况,并分析治疗因素同妊娠结局之间的关系。结果:观察组足月分娩率为93.33%,对照组为42.86%;观察组先天梅毒儿4例,对照组10例,两组足月分娩率及先天梅毒儿发生率比较差异均有统计学意义(P<0.05)。治疗时间越早,先天梅毒儿的发生率越低。结论:影响妊娠结局的治疗因素是治疗开始的孕周及用药,及时有效的全程抗梅毒治疗是预防梅毒新生儿发生率的有效手段。

Objective：To study the relationship of treatment factors and pregnancy outcome in pregnant women with syphilis. Method： From December 2009 to December 2011, 58 cases of syphilis in pregnant women were elected, pregnancy did not implement the resistance of syphilis treatment as control group, a total of 28 cases of pregnant women, pregnancy the implementation of syphilis treatment as research group, a total of 30 cases of pregnant women, comparative analysis of the two groups and infants pregnancy outcome, and treatment with the pregnancy outcome factors analysis of the relationship between them.Result：By comparison the observation group term is used for 93.33%, 42.86% for the control group term is used, the observation group congenital syphilis son 4 cases and control congenital syphilis son 10 cases, the comparative differences are significant （ P〈0.05 ）, treatment time earlier, congenital syphilis son the lower the incidence of. Conclusion：The influence of the pregnancy outcome treatment factor is the treatment began weeks of gestation and drug use, timely and effective treatment in the whole process of the resistance is to prevent syphilis neonatal syphilis rate effective means.