无口腔保健干预牙菌斑液成分的研究

Study on composition of plaque fluid in individuals with no oral hygiene

目的 研究长期无口腔保健干预的牙菌斑液糖代谢规律及其致龋力。方法 选择长期不刷牙者 43人 ,分为无龋组 2 7人 ,高龋组 16人 ,采集 10 %蔗糖漱口前后的菌斑 ,检测菌斑提取液的pH值、有机酸和无机离子的浓度。结果 糖漱口后 ,长期菌斑提取液的pH值、铵离子浓度降低 ,乳酸、甲酸升高 ,与禁食后新形成菌斑的糖代谢规律一致。但糖漱口前后两组菌斑提取液中的单一成分差异均无显著性。结论 长期菌斑与短期菌斑的糖代谢规律基本一致 。

Objective To study the change of composition in long term plaque fluid after sucrose rinse and the cariogenicity of plaque Methods 43 subjects, who had no regular oral hygiene and no tooth brushing at least for one year, were selected According to their caries status, 27 as caries free group and 16 as caries positive group Plaque were obtained before and at 7 minutes after a 10% sucrose rinse Additionally, plaque samples of 15 and 30 minutes after sucrose rinse from 11 subjects were collected The pH value and the concentrations of organic acids and inorganic ions in plaque fluid were measured Results At 7 minutes after sucrose rinse, pH and the concentration of ammonium were significantly decreased, and the concentrations of lactic acid and formic acid were significantly increased All these changes were similar to those of short term plaque No significant difference with any single component of plaque fluid was found between caries free group and caries positive group, neither before sucrose rinse nor after sucrose rinse Conclusions Changes of the composition in the plaque fluid were basically similar between long term and short term plaque, but single component in plaque fluid could not reflect the cariogenicity of plaque