原发性高血压患者窦性心律震荡的临床研究

目的探讨原发性高血压及合并左心室肥厚患者窦性心律震荡(HRT)的变化情况及临床意义。方法选择伴室性期前收缩的原发性高血压患者92例,根据彩色超声心动图结果分为:(1)原发性高血压左心室肥厚组(高血压I组47例);(2)原发性高血压无左心室肥厚组(高血压II组45例);另选45例正常健康人群为对照组。全部记录24h动态心电图窦性心律震荡检测(HRT),分别计算震荡初始(TO)和震荡斜率(TS)。结果高血压I组与Ⅱ组、对照组比较,TO值升高,TS值下降,均有显著性差异(P<0.01);高血压I组以HRT3类为主占53%,高血压Ⅱ组以HRT2类为主占51%。结论原发性高血压患者的HRT现象减弱,合并左心室肥厚时自主神经功能受损明显,HRT检测可作为评价原发性高血压患者自主神经功能状态及预后预测的指标之一。

Objective To explore and essential hypertension with left ventricular hypertrophy patients sinus heart rate shock （HRT） changes and clinical significance. Methods Choice of ventricular premature beats in patients with essential hypertension 92 cases, according to the color ultrasound heartbeat graph results classified： （1）The essential hypertension with left ventricular hypertrophy group （hypertension I group 47 cases）; （2）The essential hypertension without left ventricular hypertrophy group （hypertension II group 45 cases）; Another 45 healthy people as control group. All records of 24 hour dynamic electrocardiogram of sinus heart rate turbulence detection（HRT）,were calculated turbulence onset （TO） and turbulence slope （TS）. Results Hypertension group I and group II,the control group comparison, TO increased, TS decreased, there were significant differences（P〈0.01）; Hypertension I group to HRT3 accounted for 53%, hypertension II group to HRT2 accounted for 51%. Conclusion Patients with essential hypertension HRT phenomenon is abate, With left ventricular hypertrophy in autonomic nerve function damage apparent, HRT detection can be used as evaluation of essential hypertension patients autonomic nervous function state and prognosis prediction indexes.