未见原核的卵母细胞发育形成的优质胚胎的移植价值分析

The application value of high quality embryos from non-pronuclear oocytes in the IVF/ICSI-ET cycles

目的分析优质的未见原核胚胎(0PN-E)在体外受精-胚胎移植(IVF-ET)周期中的移植价值。方法回顾性分析接受IVF助孕且无2原核胚胎(2PN-E)或2PN-E极少的98个新鲜周期,于取卵后第2天或第3天全部或部分移植优质的0PN-E,随访其生化妊娠率、临床妊娠率、着床率及继续妊娠率。结果全部或部分移植0PN-E的生化妊娠率为41.84%,临床妊娠率为35.71%,着床率24.22%,继续妊娠率75.61%。结论在IVF-ET治疗周期中,对于2PN-E极少或无2PN-E的周期,0PN-E可作为备选移植胚胎。

Objective To analyze the application value of high quality embryos derived from oocytes with non-pronuclear in in-vitro fertilization or intracytoplasmic sperm injection（IVF/ICSI） cycles.Methods Biochemistry and clinical pregnancy rate,implantation rate and ongoing pregnancy rate were studied in 98 patients who were transfered at least one embryo derived from oocytes with non-pronuclear at day2 or day3 in IVF/ICSI embryo tranfer cycles.Results The rate of biochemical pregnancy,clinical pregnancy,implantation and ongoing pregnancy were 41.84%,35.71%,24.22%,75.61%,respectively.Conclusion In IVF/ICSI cycles,if the patient has few embryos derived from oocyte with bipronuclear（2PN-E） or has no 2PN-E,embryo derived from oocyte with nonpronuclear（0PN-E） can be used as the altemative embryo to tranfer.