人工流产对孕妇丙型肝炎病毒感染的影响

Abortion for Hepatitis C Virus Infection Effect in Pregnant Women

目的 对健康孕妇进行丙型肝炎病毒 (HCV)感染的危险因素进行研究。方法 对 1995～ 1998年上海市浦南医院 2 783名健康孕妇进行HCV感染的危险因素单因素和多因素分析。结果 人工流产次数及配偶抗 HCV阳性 ,在Logistic回归模型的多因素分析中具有意义。调查中发现 ,待业无工作的孕妇中人工流产史占人工流产者的 71.82 % ,其抗 HCV感染率为 7.37% ,高于其他职业孕妇。本次调查未发现年龄、婚姻、手术、住院、吸毒史等因素与感染HCV有关。结论 人工流产是健康孕妇感染HCV的主要危险因素 ,随着人工流产次数的增加抗HCV的阳性率也增加 ,应加强对人工流产术的仪器灭菌和消毒。

Purpose To exploit the relationship between the history of abortion and the infection of viral hepatitis C in the pregnant women. Methods Risk factors for hepatitis C virus(HCV) infection were analyzed by Chi square and a multiple logistic regression analysis in 2 783 pregnant women from Shanghai Punan hospital in 1995-1998. Results The results showed that the following factors associated significantly with anti HCV seropositive rate:number of abortion,anti HCV positive of spouse.In the logistic regression analysis the prevalence rate of HCV in pregnant women who were laid off their work was 7.37%,which was higher than that of other occupational pregnant women.There was no relationship between the HCV infection and age,marital status,history of injection,operation,hospitalization and the drug abuse. Conclusions Abortion is a risk factor of HCV infection in pregnant women.The positive rate of anti HCV is increased with the number of abortion.Strengthening the sterilization and disinfection of instruments during the abortion operation is necessary.