哺乳期院内健康教育项目对母亲乳汁sIgA浓度的影响

Project of Hospital Education in Lactation Practices improves breast milk sIgA concentration

目的观察哺乳期院内健康教育项目(Hospital Education in Lactation Practices,HELP)对母乳sIgA浓度的影响。方法在施行HELP项目1年后,自2011年7月至12月采集首次分娩、足月、单胎新生婴儿健康母亲分娩后第1、2、6周的母乳,检测其sIgA浓度,并与2008年(HELP项目实施前)实验结果和同期上海地区母乳标本作比较。结果获得37例母亲分娩后第1、2、6周的母乳标本,不同时间点母乳平均sIgA浓度分别为(4.88±6.33)g/L、(1.33±1.91)g/L和(0.80±0.97)g/L,呈明显下降趋势(P<0.05)。与2008年结果比较,各阶段母乳sIgA浓度均有提高,其中第1周母乳sIgA浓度的差异有统计学意义(P<0.05)。与同期上海地区母乳比较,第1周母乳sIgA浓度的差异已无统计学意义(P>0.05),而第2、6周母乳sIgA浓度仍较低,差异有统计学意义(P<0.05)。此外,本次研究中母亲首次泌乳日为(2.14±0.89)d,比2008年提前,差异有统计学意义(P<0.05)。结论经推行HELP项目,母乳sIgA水平提高,尤其是分娩后第1周,且母亲首次泌乳的时间提前。开展该项目有利于提高母乳喂养质量。

Objective To observe the change of breast milk sIgA concentration after implementation of Project of Hos pital Education in Lactation Practices （HELP） for one year. Methods The breast milk on the first, second and sixth weeks of postpartum was collected from healthy mothers with singleton pregnancy, first delivery and term labor from July to December, 2011. The slgA concentration was detected and compared with data collected in 2008 and data collected in Shanghai at the same time. Results The breast milk on the first, second and sixth weeks of postpartum was collected from 37 mothers. The slgA concentrations were （4.88±6.33） g/L （0.01-35.29 g/L）, （1.33±1.91） g/L （0.06-18.58 g/L）, （0.80±0.97） g/L （0.01-7.11 g/L）, respectively. A downward trend was observed on slgA concentration, and the difference had statistical significance （P〈0.05）. Compared with the data in 2008, the slgA concentration was higher in samples collected in 2011, especially on the first week of postpartum, and the difference was statistically significant （P〈0.05）. Compared with the data from Shanghai, the slgA con centration was significantly lower in samples from Hobhot at each stage, except on the first week of postpartum which had no difference （P〉0.05）. The onset of lactation was （2.14±0.89） day of postpartum in 2011, earlier than that in 2008 （P〈0.05）. Con- clusions After HELP, the onset of lactation is earlier, and breast milk slgA concentration is increased, especially on the first week of postpartum. It is suggested that the promotion of HELP could improve breast milk quality.