对我国胆囊癌临床诊治现状的种种思考

Various considerations about the status quo of gallbladder cancer in China

收集国内88篇公开报道的7882例胆囊癌临床分析资料，以了解国内胆囊癌诊治概况，探讨如何面对胆囊癌诊治的相关问题。文献收集范围与要求：（1）国内1980年1月至2008年6月刊出的胆囊癌文献；（2）病例分析报告均大于50例以上；（3）病例均来自国内一家单位（医院）；（4）同一作者（单位）重复报道病例按最多病例数计。资料分析表明，原发性胆囊癌是胆道系统最常见的恶性肿瘤，女性多于男性。该病发病隐匿，临床症状不典型，早期诊断率低，恶性程度高，预后极差，病理类型以腺癌为主。虽然外科手术技术不断进步，但手术切除率仍低。文中对胆囊癌诊治几个值得关注的问题作些讨论。

To discuss the status quo of gallbladder cancer in China, 88 articles published in China were collected and the clinical data of 7882 patients who were suffering from gallbladder cancer was analyzed. The requirements for the literature were： domestic articles published from 1980.1 to 2008.6, the gallbladder cancer cases must exceed 50, the cases must come from the same domestic hospital, and if the cases were reduplicative, the maximum were selected. Anal- ysis of the data showed that primary carcinoma of the gallbladder was the most common malignant tumor in the biliary tract, with a higher incidence in females than males. The cancer＇s pathologic characteristics of undiscoverable growth and poor differentiation led to its clinical significance of difficult early stage diagnosis, high degree of malignancy, poor prognosis, and adenocarcinoma formation. Although the technique of surgical operation has constantly progressed over time, gallbladder cancer surgery possesses a lower rate of radical resection. Every biliary surgeon should brainstorm and deliberate about how to face the status quo of gallbladder cancer in China. This article participates in that discussion by identifying several noticeable problems in the diagnosis and treatment of gallbladder cancer.