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趋化因子CXCL16在心力衰竭发病机制中的研究进展

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摘要 心力衰竭（HF）是心血管疾病死亡率增加的重要原因，尽管新的治疗方案不断引进，但HF患者的死亡率仍很高。随着研究的进展，人们发现HF的病理生理过程不仅受神经内分泌系统影响，而且与炎症细胞因子的调控密切相关，而趋化因子是炎症发生、发展的过程中重要的促炎细胞因子。在众多趋化因子家族中，CXC亚族是近年来研究的热点，其中CXCL16是既能以分泌又能以膜结合形式存在的趋化因子，在心血管疾病中作用受到越来越多学者的关注，但在HF中却鲜有报道。
作者 李倩 卜丽梅
机构地区 吉林大学第一医院干部病房
出处 《中国老年学杂志》 CAS CSCD 北大核心 2012年第24期5622-5624,共3页 Chinese Journal of Gerontology
关键词 CXCL16 心力衰竭 趋化因子 发病机制
分类号 R541 [医药卫生—心血管疾病]
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参考文献15

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二级参考文献13

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中国老年学杂志
2012年 第24期

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