用激光多普勒测量间歇式正压对随意皮瓣血流的影响

Effects of intermittent positive pressure on blood supply of random flaps measured by laser Doppler flowmeter

目的 :了解间歇式正压对随意皮瓣血供的影响。方法 :4cm× 16cm大小随意皮瓣原位移植后 ,实验组给予间歇式正压至术后 7天 ,于术后 4h、1天至 7天测量远、中、近三点 (皮瓣均分三段 ,每段中点 )的激光多普勒血流 (LDF)值。观察实验组与对照组间三点总的血供量、中点血供量及近点与正常皮肤血供的差别。结果 :实验组与对照组LDF值有显著性差异 ,实验组随意皮瓣血供比对照组的好 ,血供总量差异第 2～ 7天出现 ;中间测量点第 3～ 7天均有显著差异 ;实验组近测量点血供术后 2天与正常皮肤的LDF值无显著差异 ,比对照组早一天。结论 :间歇式正压改善了随意皮瓣的血供 ,使血供总量提高 。

Objective:To investigate the effects of intermittent positive pressure (IPP) on blood supply(BS) of random flaps.Methods:4 cm×16 cm size random flaps of pig were grafted in site and treated by IPP with continuous pressure 7.5 kPa for 1 min in an interval of 4 min.Each flap was divided into three parts.BS of middle spot on every part was measured from 4 h to 7 d after operation with laser Doppler flowmeter(LDF).The total and middle part BS were observed and compared between experimental and control groups,and the near part BS of two groups were compared with normal skin.Results:BS of experimental group showed significant better than that of control group,which was found in the total BS by 2 d postoperation and in middle part BS 3 d respectively.BS of normal skin had no obvious difference from experimental group 2 d postoperation and from control group 3 d after operation.Conclusion:IPP can improve the BS of random flap.This might involve enhancing the recovery of middle part BS and increasing total BS.