钩藤提取工艺研究

Study on Extraction Technology of Ramulus uncariae cum uncis

目的 :筛选制定出确保钩藤制剂质量的提取工艺。方法 :用薄层扫描法对钩藤在常规制剂中所用的水煮浓缩法及70 %～ 75 %乙醇提取法提取的钩藤有效成分进行了定量比较。结果 :用 70 %乙醇提取的钩藤有效成分含量明显高于水提液。结论 :浓缩、干燥温度应低于 81°C。

Objective: To investigate the influences of different extraction conditions on the active components of Ramalus uncariae cum uncis, and select an extraction method which could ensure the preparation quality. Methods: The active components of Ramluo uncariae cum uncis extracted by water and by 70%～75% alcohol from the routine proparations were quantitatively compared by TCL scanning. Results: The active component content extracted by 70% alcohol was higher. Conclusion: 70% alcohol extraction is the best way of obtaining the highest content of active component of Ramulus uncariae cum uncis. When the active component is extracted by water, it is preferable that the extraction time dosen't longer than half an hour.