摘要
目的 :研究甘芍注射液对小鼠实验性肝损伤的保护作用。方法 :采用化学毒物D 半乳糖胺和四氯化碳致小鼠肝脏损伤 ,测定生化指标及观察病理组织学改变。结果 :甘芍注射液呈剂量依赖性地明显降低D 半乳糖胺、四氯化碳引起的小鼠血清ALT和AST增高 ;病理组织学检查表明甘芍注射液明显减轻肝细胞的变性和坏死。结论 :甘芍注射液对小鼠实验性肝损伤有明显的保护作用。
Objective:To investigate the protective effects of Ganshao Injection on experimental liver injury in mice.Mothods:The biochemical indexes and histopathological charges of liver injury in mice caused by toxicant chemicals [D galactosamine(D Galn) and CCl 4] were determined.Results:Ganshao Injection obviously dose dependently inhibited the rising of serum ALT and AST caused by D Galn and CCl 4. Histopathological examination showed that Ganshao Injection could evidently alleviate the condition and necrosis of the degeneration of hepatic cells.Conclusion:Ganshao Injection is of obviously protective effects on experimental liver injury in mice.
出处
《中成药》
CAS
CSCD
2000年第5期358-360,共3页
Chinese Traditional Patent Medicine
