小儿肺炎继发腹泻的相关因素分析

Relevant factors of diarrhea secondary to pneumonia in children

目的探讨影响小儿肺炎继发腹泻的相关因素,为临床干预提供依据。方法按是否继发腹泻,将535例小儿肺炎患者分为两组:腹泻组(n=237)与非腹泻组(n=298)。采用χ2检验进行单因素分析,然后选择有统计学意义的相关因素进行非条件Logistic回归分析。结果①单因素分析发现,两组患儿的年龄、住院时间、中性粒细胞比值、病情严重程度、侵入性操作、抗生素使用时间、激素治疗、多种抗生素联合使用、微生态制剂治疗相比差异有统计学意义(P<0.05)。②经Logistic回归分析发现,年龄、住院时间、侵入性操作、激素治疗、多种抗生素联合使用是导致小儿肺炎继发腹泻的独立危险因素,微生态制剂治疗则是独立保护因素(P<0.05)。结论根据相关因素的分析结果,我们可以采取相应的干预措施降低小儿肺炎继发腹泻的发生率。

Objective To investigate the relevant factors of diarrhea secondary to pneumonia in children, and provide basis for clinical intervention. Methods According to with or without secondary diarrhea,535 children with pneumonia were as- signed to diarrhea group （n = 237） and non-diarrhea group （n = 298）,and relevant factors were analyzed by univariate analysis and logistic regression analysis. Results （1） The univariate analysis found that there were significant differences in age,hospital stay,neutrophil granulocyte ratio,disease severity,invasive procedures, duration of antibiotic treatment,hor- mone therapy,joint use of multiple antibiotics and probiotic therapy between diarrhea group and non-diarrhea group. （2） The logistic regression analysis found that age,hospital stay,invasive procedures,hormone therapy,joint use of multiple antibiotics were independent risk factors for diarrhea secondary to pneumonia in children,while probiotic therapy was an independent protective factor. Conclusion According to the analysis results of relevant factors, we should take effective measures against diarrhea secondary to pneumonia in children.