反刍动物体内共轭亚油酸生物合成途径研究进展

Progresses in the biosynthesis pathways of conjugated linoleic acids in ruminants

共轭亚油酸是一组共轭双键具有不同位置和几何构象的亚油酸异构体,主要存在于反刍动物的肉及乳中。本文就其中2种具有重要生理功能的共轭亚油酸(c-9,t-11CLA和t-10,c-12CLA)的生物合成途径的研究进行综述,以期了解共轭亚油酸代谢途径及其调控路径,为今后利用合成生物学指导共轭亚油酸的合成奠定基础。

Conjugated linoleic acid is a mixture of positional and geometric isomers of linoleic acid with two conjuga- ted unsaturated double bonds at various carbon positions in the fatty acid chain, mainly found in the milk and meat of ruminants. 2 of them （ c - 9, t - 11 CLA and t - 10, c - 12 CLA） with physiological importance were reviewed in