期刊文献+

阿尔茨海默病与轻度认知功能障碍的相关研究进展

下载PDF
导出
摘要 阿尔茨海默病(Alzheimer’s disease,AD)是一种进行性神经系统变性疾病,是老年最常见的痴呆类型。轻度认知功能障碍(mild cognitive impairment,MCI)被普遍认为是痴呆的早期状态,且被证实有可逆性。如果在该阶段就能给予干预治疗,有可能降低AD的发病率。本文对可能影响MCI的因素以及相关研究进展进行回顾与综述,希望对AD的早期诊断有所帮助。
作者 尤玥 李子建
机构地区 中国医科大学
出处 《中国老年保健医学》 2012年第6期67-68,共2页 Chinese Journal of Geriatric Care
  • 相关文献

参考文献20

  • 1Lee TS, Krishnan KR. Alzheimer' s disease-the inexorable epidemic [ J ]. Ann Acad Med Singapore, 2010,39 (7) :505.
  • 2Petersen RC, Clinic M, Rochester MN. Mild cognitive impairment transition from aging to Alzheimer' s disease [ J ]. Neurobiol Aging, 2000,15(3) :93 - 101.
  • 3Schaaf RC, Miller IJ. Occupational therapy using a sensory integrative approach for children with developmental disabilities [ J ]. Ment retard Dev Disabil Rev, 2005,11 (2) :143 -148.
  • 4De Pascalis V, Arwari B, D Antuono L, et al. Impulsivity and seman- tic/emotional processing; an examination of the N400 wave [ J]. Clini- cal Neurophysiology, 2009,120 ( 1 ) :85 - 92.
  • 5Cechetto DF, Hachinski V, Whitehead SN. Vascular risk factors and Alzheimer' s disease [ J]. Expert Rev Neurother, 2008,8 (5) :743.
  • 6Grossman H. Does diabetes protect or provoke Alzheimer's disease? In- sights into the pathobiology and future treatment Of Alzheimer's disease [J]. CNS Spectr, 2003,8:815 -823.
  • 7Moreira PI, Santos MS, Seica R, et al. Brain mitochondrial dysfunc- tion as a link between Alzheimer's disease and diabetes [J]. J Neurol Sci, 2007,257:206 -214.
  • 8Arvanitakis Z, Schneider JA, Wilson RS, et al. Diabetes is related to cerebral infarction but not to AD pathology in older persons [ J ]. Neu- rology, 2006,67:1960 - 1965.
  • 9Kim J, Basak JM, Holtzman DM. The role of apolipoprotein E in Alzheimer's Disease [ J]. Neuron, 2009,63 (3) : 287 - 303.
  • 10Farlow MR, He Y, Tekin S, et al. Impact of APOE in mild cognitive impairment [ J ]. Neurology, 2004,63 (10) : 1898 - 1901.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部