摘要
目的分析临床资料,总结原发性胆汁性肝硬化(PBC)患者的临床表现和病理特征。方法对86例PBC患者的临床资料进行回顾性分析。结果 86例PBC患者临床主要表现为黄疸(60%),尿黄(51%),腹胀(30%),皮肤瘙痒(20%)。患者ALP和GGT水平明显升高,分别为(239.6±139.2)U/L和(253.6±225.1)U/L,ALT和AST轻度升高,平均为(197.2±284.9)U/L和(167.9±174.1)U/L。48%的患者IgM水平明显升高,平均为(3.6±2.4)g/L,67%的AMA-M2阳性和61%的ANA阳性。结论 ALP、GGT、AMA-M2和ANA有利于PBC的早期诊断,这样有利于延缓病情和改善预后。
Objective To analyze the features of clinic,biochemistry,immunology and pathology in primary biliary cirrhosis.Methods General status,clinical manifestations and of 86 patients with PBC were reviewed.Results The most frequently complained symptoms were jaundice（60%）,fatigue（54%）,ascites（30%）andpruitus（20%）.ALP and GGT levels were remarkably elevated in majority patients（239.6 ±139.2）U/L and（253.6 ±225.1）U/L,whereas ALT and AST levels were mildly to moderately elevated（197.2±284.9）U/L and（167.9±174.1）U/L.34.2 tLmol / L.41 patients（48%） had elevated serum IgM and 58 patients（67%） were antimitochondrial anti-body（AMA）/AMA-M2 positive.Conclusion Elevated serum ALP and GGT levels together with positive AMA/ AMA-M2 can help to diagnose.
出处
《中外医疗》
2012年第33期92-92,94,共2页
China & Foreign Medical Treatment
关键词
原发性胆汁肝硬化
临床表现
治疗
Primary biliary cirrhosis
Clinical research
Treatment
