注射用水冷回路在制药工程项目中的设计和应用

Design of Cold Loop of Water for Injection and Its Application in Pharmaceutical Engineering

注射用水(WFI)的冷却子回路在生物制药中的应用非常普及。在本文中笔者将其整理和归纳为五种方案,即直排冷分支、带泵子循环、独立冷循环、节流分回路和单点冷却器方案,通过对这五种型式在设计和应用方面的说明、比较、评估和探讨,为同行提供一些初步的参考和交流。

The application of cold sub-loop of water for injection （WFI） is popular in pharmaceutical industry. In this article, the author arranged and induced five schemes, which are single cooler branch, sub-loop with pump, single sub cold loop, throttling sub-loop and POU cooler. Through the explanation, comparison, evaluation and discussion for these schemes, the references were presented.