肝癌外科的远期疗效——104例生存5年以上病例分析

LONG-TERM RESULTS AFTER SURGERY FOR HEPATOCELLULAR CARCINOMA. REPORT OF 104 PATIENTS SURVIVED OVER5 YEARS

本文报道104例病理证实肝细胞肝癌外科治疗后生存5年以上病例,其中96例系肝癌手术切除病例、8例系肝动脉结扎和/或插管化疗病例。全组亚临床期占47.1(49/104)、中期占52.9％(55/104),瘤体≤5cm者51例。合并肝硬化占80.8％(84/104)。根治性切除占95.8％(92/96)。至1991年2月,72.9％(70/96)肝癌切除病例无癌健在,75.0％(6/8)肝动脉结扎和/或插管化疗病例带瘤生存。36例术后生存10年以上,最后1例肝癌切除术后已29年3个月,仍健在。长期健在患者中多数已恢复工作,3例青年患者术后已结婚生育。本文对提高肝癌外科的远期疗效进行了讨论。

A total of 104 cases with pathologically proven hepatocellular carcinoma (HCC) survived over 5 years were collected from. Feb. 1961. to Feb. 1986. of them, 96 cases received resection of HCC and 8 cases received hepatic artery ligation(HAL) and/or infusion chemotherapy(HAI).Subclinical stage amounted to 47.1% (49/104) and moderate stage to 52.9% (55/104). There were 51 cases with small HCC(≤5cm). Cirrhosis was present in 80.8% (84/104). Radical resection was performed lin 95.8% (92/96). By the end of Feb. 1991, 72.9% of the the patients (70/96) who received resection of HCC are still alive and free of disease; and 75.0% of the patients(6/8) who received HAL and/or HAI are still alive with disease. 36 of 104 patients survived over 10 years, including 1 patient received HAI. One patient has survived for 29 years and 3 months after resection of HCC (alive). The majority of long-term survivors have returned to their original work; 3 young patients got married after resection of HCC. Some aspects to improve long-term survival are discussed.