从“久病入络”论干燥综合征病理演变

Theoretical Studies on the Pathological Change of Sjogren's Syndrome from Theory of Prolonged llness Entering into Venation

干燥综合征是一种慢性进展性疾病,具有病程长、病机变化复杂的特点。初期多为阴虚津亏,随着病情的进展,阴津渐乏,内热渐生,燥热越重。病久津液不复,则病邪入深脏腑、经络,闭阻经脉,五脏气机紊乱,升降无序,津液运行失调,敷布失常,脏腑诸窍失于濡润。因此,久病入络的理论揭示了干燥综合征病理演变和转归的总趋势,表明其发展到一定阶段,必然存在络脉的病理病变,是其病情缠绵,久发难愈的根源。

Sjogren＇s syndrome is a chronic progressive disease,with a long course and complex pathogenesis.Early stage is due to Yin-deficiency and depletion of fluid,as the disease progresses,Yin-fluid becomes depleted.Yin-fluid can not be restored if the disease period is long,evil Qi can enter into the deep organs and meridians,leading to Zang-organs Qi disorder,body fluid running disorders.Therefore,theory of prolonged illness entering into colleterals reveals the pathological evolution and development trend of sjogren＇s syndrome.So there must be pathological lesion when it develops to a certain stage.It is also the reason of the long course and refractory essence of sjogren＇s syndrome.