ENBD治疗ERCP后胆管感染及高淀粉酶血症疗效分析

Effects of ENBD Treating Post-ERCP Biliary Tract Infection and Hyperamylasemia

目的评价内镜鼻胆管引流术(ENBD)治疗经内镜逆行胰胆管造影(ERCP)术后胆管感染和高淀粉酶血症疗效。方法选择行ERCP胆总管结石患者120例,其中术后未给予ENBD60例作为对照组,术后给予ENBD60例作为治疗组。结果治疗组和对照组血清淀粉酶值和C反应蛋白值在术前比较,差异无统计学意义(P>0.05),术后3 h和24 h对比,差异有统计学意义(P<0.01),治疗组优于对照组。同时,治疗组胆管感染和高淀粉酶血症发生率均低于对照组,差异有统计学意义(P<0.05)。结论鼻胆管引流术对ERCP术后胆管感染和高淀粉酶血症均有一定的预防作用。

Objective To evaluate endoscopic naso-biliary drainage（ENBD）effect on post-ERCP biliary tract infection and hyperamylasemia.Methods 120 cases with common bile duct stones for routine ERCP were selected,among which 60 cases not given ENBD were set as the control group,the other 60 cases given ENBD were set as the treatment group.Results After observation,amylase and CRP levels of the two groups were not statistically significantly different from before surgery（P0.05）,while significant differences were seen between 3 hours after surgery and 24 hours after surgery（P0.01）,the treatment group better than the control group.The biliary tract infection and hyperamylasemia rates in the treatment group were lower than that in the control group（P0.05）.Conclusion ENBD treatment has a certain preventive function on post-ERCP biliary tract infection and hyperamylasemia.