摘要
用硅胶柱色谱、Sephadex LH-20凝胶柱色谱等色谱技术分离纯化窄叶鲜卑花的化学成分,通过理化方法和波谱数据确定化合物结构.从窄叶鲜卑花二氯甲烷浸膏中分离并鉴定了9个化合物:香草醛(1)、甲基阿魏酸(2)、对甲氧基桂皮酸(3)、N,N′-二环己基脲(4)、Valencic acid(5)、ω-羟基-3-甲氧基-4-羟基苯乙酮(6)、异阿魏酸(7)、咖啡酸(8)及3,4-二羟基苯甲酸(9),除化合物2、7及8外,其他化合物都为从该植物中首次报道,化合物5及6首次从蔷薇科得到,化合物4首次从植物体内得到.以上结果可为该药材的进一步研究开发提供参考.
Chemical constituents of dichloromethane extract of Sibiraea angustata (Rehd.) Hand.-Mazz. were isolated and purified by silica gel and Sephadex LH-20 column chromatography and determined with physichemical and spectral methods. Nine compounds were obtained and identified as vanillin (1), methyl ferulic acid (2), p-methoxy cinnamic acid (3), N, N'-dicyclohexylurea (4), valencic acid (5), ω- hydroxypropiovanillone (6), isoferulic acid (7), caffeic acid (8) and 3, 4-dihydroxybenzoic acid (9). Compounds other than 2, 7 and 8 were all reported for the first time from this plant. Compound 5 and 6 were obtained from family Rosaceae for the first time, and compound 4 obtained from plants for the first time. Such data are useful for further research and development.
出处
《北京师范大学学报(自然科学版)》
CAS
CSCD
北大核心
2012年第6期621-625,共5页
Journal of Beijing Normal University(Natural Science)
基金
公益性行业(农业)科研专项资金资助项目(201103027)
"重大新药创制"科技重大专项资金资助项目(2011ZX09307-002-01)
关键词
窄叶鲜卑花
化学成分
提取分离
结构鉴定
Sibiraea angustata (Rehd.) Hand.-Mazz
chemical constituents
extraction and isolatiomstructure identification