肌钙蛋白、心肌酶谱联合脑钠肽对急性心梗患者的诊断价值

Diagnostic value of troponin, myocardial enzymes, brain natriuretic peptide to acute myocardial infarction patients

目的研究肌钙蛋白(cTnI,cTnT)、心肌酶谱联合脑钠肽对急性心肌梗死(acute myocardialinfarction,AMI)的诊断价值。方法住院的AMI患者104例,正常对照组来自我院体检科60例。研究两组之间的肌钙蛋白、心肌酶谱联合脑钠肽指标的应用价值。结果 AMⅠ组治疗前和对照组之间的心肌酶指标包括谷草转氨酶(AST)、肌酸激酶(CK)、肌酸激酶同工酶(CKMB)、乳酸脱氢酶(LDH),心梗指标包括肌红蛋白Mb、cTnI、cTnT,以及新指标脑钠肽(brain natriuretic peptide,BNP)在两组之间的差异明显(P<0.05)。BNP、BNP/AST、BNP/CKMB、BNP/cTnT以及BNP/cTnI的曲线下面积均大于0.90,对治疗前急性心梗的诊断价值较高。指标的诊断价值排序为:BNP/cTnT>BNP/cTnI>BNP/CKMB>BNP/AST>BNP。结论 BNP、BNP/AST、BNP/CKMB、BNP/cTnT以及BNP/cTnI的对急性心梗的诊断价值较高。

Objective To study diagnostic value of the study troponin （cTnI, cTnT）, myocardial enzymes, brain natriuretic peptide to acute myocardial infarction. Methods 104 cases of hospitalized patients with AMI and 60 cases of normal control group from the hospital physical examination department.Research the application value of troponin, myocardial enzymes, brain natriuretic peptide between the two groups. Results AMI group before treatment and control group were significant differences in aspartate aminotransferase, creatine kinase, creatine kinase MB, lactate dehydrogenase, myocardial infarction indicators include myoglobin Mb, cTnI, cTnT, as well as new indicators of brain natriuretic peptide （P0.05）. BNP, BNP/AST, BNP/CKMB, BNP/cTnT and BNP/cTnI area under the curve were greater than 0.90, the diagnosis was high before the treatment of acute myocardial infarction. The diagnostic value of sort of targets： BNP/cTnT BNP/cTnI BNP/CKMB BNP/AST BNP. Conclusion BNP, BNP/AST, BNP/CKMB, BNP/cTnT and BNP/cTnI have high value in the diagnosis of acute myocardial infarction.