固体酸催化合成异山梨醇的研究

Study on Preparation of Isosorbitol Using Solid acid Catalyst

以对甲苯磺酸为催化剂、甲苯为带水剂,山梨醇脱水制备异山梨醇,产品质量符合日本药典XV质量标准,收率约为50%。

To prepare isosorbitol by dehydration reaction of sorbitol with p-toluenesulfonic acid as the catalyst, tolu- ene as dehydrating agent. The product quality reached Japanese standards, the yield was 50%.